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An overview of common anorectal conditions
Wednesday 1 February 2023, 12:15 AM

[Image: iStock.com – AtlasStudio]
Benign anorectal conditions are very common, and patients may go to pharmacies looking for over-the-counter therapies. Pharmacists will find this article, written by colorectal and general surgeon Sze-Lin Peng, useful for prescribing initial topical treatments and advising patients to get a medical assessment
There is a wide variety of anorectal symptoms and complaints. Benign and malignant conditions may present with similar symptoms, and can also coexist,
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References
- Olde Bekkink M, McCowan C, Falk GA, et al. Diagnostic accuracy systematic review of rectal bleeding in combination with other symptoms, signs and tests in relation to colorectal cancer. Br J Cancer 2010;102(1):48–58.
- Araghi M, Soerjomataram I, Bardot A, et al. Changes in colorectal cancer incidence in seven high-income countries: a population-based study. Lancet Gastroenterol Hepatol 2019;4(7):511–18.
- Riss S, Weiser FA, Schwameis K, et al. The prevalence of hemorrhoids in adults. Int J Colorectal Dis 2012;27(2):215–20.
- Song M, Emilsson L, Bozorg SR, et al. Risk of colorectal cancer incidence and mortality after polypectomy: a Swedish record-linkage study. Lancet Gastroenterol Hepatol 2020; 16 March online.
- Giacosa A, Frascio F, Munizzi F. Epidemiology of colorectal polyps. Tech Coloproctol 2004;8, Supp.2:243–47.
- Gardner IH, Siddharthan RV, Tsikitis VL. Benign anorectal disease: hemorrhoids, fissures, and fistulas. Ann Gastroenterol 2020;33(1):9–18.
- Coughlin OP, Wright ME, Thorson AG, et al. Hemorrhoid banding: A cost-effectiveness analysis. Dis Colon Rectum 2019;62(9):1085–94.
- Nelson RS, Thorson AG. Risk of bleeding following hemorrhoidal banding in patients on antithrombotic therapy. Gastroenterol Clin Biol 2009;33(6–7):463–65.
- Xia W, Manning JPR, Barazanchi AWH, et al. Metronidazole following excisional haemorrhoidectomy: a systematic review and meta-analysis. ANZ J Surg 2018;88(5):408–14.
- Altomare DF, Binda GA, Canuti S, et al. The management of patients with primary chronic anal fissure: a position paper. Tech Coloproctol 2011;15(2):135–41.
- Nelson RL, Thomas K, Morgan J, et al. Non surgical therapy for anal fissure. Cochrane Database Syst Rev 2012;(2):CD003431.
- National Library of Medicine (US). Drugs and Lactation Database. Nifedipine.
- Sahebally SM, Walsh SR, Mahmood W, et al. Anal advancement flap versus lateral internal sphincterotomy for chronic anal fissure- a systematic review and meta-analysis. Int J Surg 2018;49:16–21.
- Muhlmann MD, Hayes JL, Merrie AE, et al. Complex anal fistulas: plug or flap?. ANZ J Surg 2011;81(10):720–24.
- Mitalas LE, Gosselink MP, Zimmerman DD, et al. Repeat transanal advancement flap repair: impact on the overall healing rate of high transsphincteric fistulas and on fecal continence. Dis Colon Rectum 2007;50(10):1508–11.