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Kiwi researchers start to uncover vitamin C’s potential as cancer fighter
Saturday 1 May 2021, 01:10 AM
University of Otago associate professor Gabi Dachs
In a world first, New Zealand scientists have shown that vitamin C, in high-dose infusions, infiltrates cancer tumours. Fiona Cassie finds out what this means for the unproven, but popular, complementary therapy
High-dose vitamin C infusions can get into cancer tumours even though the vitamin C quickly disappears from patients’ bloodstreams, a Christchurch res
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References
- Dachs GU, Gandhi J, Wohlrab C et al. Vitamin C administration by intravenous infusion increases tumor ascorbate content in patients with colon cancer: a clinical intervention study. Frontiers in Oncology 2021;10:2984. Online 11 January.
https://www.frontiersin.org/articles/10.3389/fonc.2020.600715/full - Campbell EJ, Dachs GU, Morrin HR et al. Activation of the hypoxia pathway in breast cancer tissue and patient survival are inversely associated with tumor ascorbate levels. BMC Cancer 2019;19:307. Online 3 April 2019. https://doi.org/10.1186/s12885-019-5503-x
- Kuiper C, Dachs G, Munn D et al. Increased tumor ascorbate is associated with extended disease-free survival and decreased hypoxia-inducible factor-1 activation in human colorectal cancer. Frontiers in Oncology 2014;4:10. Online 4 February 2014. https://pubmed.ncbi.nlm.nih.gov/24551593/
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