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Herbal remedies for menopause
Wednesday 1 February 2023, 12:30 AM
Black cohosh is one of the most popular plant extracts for menopause
There’s a plethora of plants and herbs that can help menopausal women – it’s just a case of finding the right ones to suit the patient, writes pharmacist and medical herbalist Phil Rasmussen
The use of natural health products by women experiencing symptoms of menopause and the menopause transition (perimenopause) is very common. Manifestat
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References
- Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women’s Health Initiative randomized controlled trial. JAMA 2002;288:321–33.
- Anderson GL, Limacher M, Assaf AR, et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: The Women’s Health Initiative randomized controlled trial. JAMA 2004;291:1701–12.
- Beral V; Million Women Study Collaborators. Breast cancer and hormone-replacement therapy in the Million Women Study. Lancet 2003;362(9382):419–27.
- Cagnacci A, Venier M. The controversial history of hormone replacement therapy. Medicina (Kaunas) 2019;55(9):602.
- Mahady GB, Low Dog T, Barrett ML, et al. United States Pharmacopeia review of the black cohosh case reports of hepatotoxicity. Menopause 2008;15(4 Pt 1):628–38.
- Teschke R, Bahre R, Fuchs J, Wolff A. Black cohosh hepatotoxicity: quantitative causality evaluation in nine suspected cases. Menopause 2009;16(5):956–65.
- Leach MJ, Moore V. Black cohosh (Cimicifuga spp.) for menopausal symptoms. Cochrane Database Syst Rev 2012;2012(9):CD007244.
- Beer AM, Osmers R, Schnitker J, et al. Efficacy of black cohosh (Cimicifuga racemosa) medicines for treatment of menopausal symptoms - comments on major statements of the Cochrane Collaboration report 2012 “black cohosh (Cimicifuga spp.) for menopausal symptoms (review)”. Gynecol Endocrinol 2013;29(12):1022–25.
- Wuttke W, Jarry H, Haunschild J, et al. The non-estrogenic alternative for the treatment of climacteric complaints: Black cohosh (Cimicifuga or Actaea racemosa). J Steroid Biochem Mol Biol 2014;139:302–10.
- Booth NL, Piersen CE, Banuvar S, et al. Clinical studies of red clover (Trifolium pratense) dietary supplements in menopause: a literature review. Menopause 2006;13(2):251–64.
- Kanadys W, Barańska A, Błaszczuk A, et al. Evaluation of clinical meaningfulness of red clover (Trifolium pratense L.) extract to relieve hot flushes and menopausal symptoms in peri- and post-menopausal women: A systematic review and meta-analysis of randomized controlled trials. Nutrients 2021;13(4):1258.
- Bommer S, Klein P, Suter A. First time proof of sage’s tolerability and efficacy in menopausal women with hot flushes. Adv Ther 2011;28(6):490–500.
- Dadfar F, Bamdad K. The effect of Saliva officinalis extract on the menopausal symptoms in postmenopausal women: An RCT. Int J Reprod Biomed 2019;17(4):287–92.
- Koubaa-Ghorbel F, Chaâbane M, Jdidi H, et al. Salvia officinalis mitigates uterus and liver damages induced by an estrogen deficiency in ovariectomized rats. J Food Biochem 2021;45(5):e13542.
- Chen LC, Wang BR, Chen IC, Shao CH. Use of Chinese herbal medicine among menopausal women in Taiwan. Int J Gynaecol Obstet 2010;109(1):63–66.
- Kang EY, Kim HK, Jung JY, et al. Combined extract of Leonurus japonicus Houtt, Eclipta prostrata L., and Pueraria lobata Ohwi improved hot flashes and depression in an ovariectomized rat model of menopause. Foods 2021;10(1):180.
- Kim J, Kim MH, Choi YY, et al. Inhibitory effects of Leonurus sibiricus on weight gain after menopause in ovariectomized and high-fat diet-fed mice. J Nat Med 2016;70(3):522–30.
- Chen B, Wang L, Li L, et al. Fructus Ligustri Lucidi in osteoporosis: A review of its pharmacology, phytochemistry, pharmacokinetics and safety. Molecules 2017;22(9):1469.
- Deng YT, Kang WB, Zhao JN, et al. Osteoprotective effect of echinocystic acid, a triterpone component from Eclipta prostrata, in ovariectomy-induced osteoporotic rats. PLoS One 2015;10(8):e0136572.
- Chen HY, Lin YH, Wu JC, et al. Prescription patterns of Chinese herbal products for menopausal syndrome: analysis of a nationwide prescription database. J Ethnopharmacol 2011;137(3):1261–66.
- Abdi F, Mobedi H, Roozbeh N. Hops for menopausal vasomotor symptoms: Mechanisms of action. J Menopausal Med 2016;22(2):62–64.
- Keiler AM, Zierau O, Kretzschmar G. Hop extracts and hop substances in treatment of menopausal complaints. Planta Med 2013;79(7):576–79.
- Štulíková K, Karabín M, Nešpor J, Dostálek P. Therapeutic perspectives of 8-prenylnaringenin, a potent phytoestrogen from hops. Molecules 2018;23(3):660.
- Kim HI, Kim MK, Lee I, et al. Efficacy and safety of a standardized soy and hop extract on menopausal symptoms: A 12-week, multicenter, randomized, double-blind, placebo-controlled clinical trial. J Altern Complement Med 2021;27(11):959–67.
- Fritz H, Seely D, Flower G, et al. Soy, red clover, and isoflavones and breast cancer: a systematic review. PLoS One 2013;8(11):e81968.
- Molaie M, Darvishi B, Jafari Azar Z, et al. Effects of a combination of Nigella sativa and Vitex agnus-castus with citalopram on healthy menopausal women with hot flashes: results from a subpopulation analysis. Gynecol Endocrinol 2019;35(1):58–61.
- Farshbaf-Khalili A, Farajnia S, Pourzeinali S, et al. The effect of nanomicelle curcumin supplementation and Nigella sativa oil on the expression level of miRNA-21, miRNA-422a, and miRNA-503 gene in postmenopausal women with low bone mass density: A randomized, triple-blind, placebo-controlled clinical trial with factorial design. Phytother Res 2021;35(11):6216–27.
- Eatemadnia A, Ansari S, Abedi P, Najar S. The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial. Complement Ther Med 2019;45:109–13.
- Liu YR, Jiang YL, Huang RQ, et al. Hypericum perforatum L. preparations for menopause: a meta-analysis of efficacy and safety. Climacteric 2014;17(4):325–35.
- van Die MD, Bone KM, Burger HG, et al. Effects of a combination of Hypericum perforatum and Vitex agnus-castus on PMS-like symptoms in late-perimenopausal women: findings from a subpopulation analysis. J Altern Complement Med 2009;15(9):1045–48.
- Laakmann E, Grajecki D, Doege K, et al. Efficacy of Cimicifuga racemosa, Hypericum perforatum and Agnus castus in the treatment of climacteric complaints: a systematic review. Gynecol Endocrinol 2012;28(9):703–09.
- Franco OH, Chowdhury R, Troup J, et al. Use of plant-based therapies and menopausal symptoms: A systematic review and meta-analysis. JAMA 2016;315(23):2554–63.
- Kenda M, Glavač NK, Nagy M, et al. Herbal products used in menopause and for gynecological disorders. Molecules 2021;26(24):7421.
- Mehrnoush V, Darsareh F, Roozbeh N, Ziraeie A. Efficacy of the complementary and alternative therapies for the management of psychological symptoms of menopause: A systematic review of randomized controlled trials. J Menopausal Med 2021;27(3):115–31.
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